By C.M. Poser
This can be a thoroughly new, completely updated colour atlas-textbook of a number of sclerosis (MS). the 1st of its sort, it deals particular price for its illustrations and instructive textual content at the very newest diagnostic strategies for MS. The ebook opens with introductory and historical past info after which covers the pathogenesis of MS regarding alteration of the blood-brain barrier. The part on analysis covers IgG and oligoclonal bands within the cerebrospinal fluid; evoked power stories, together with visible, brainstem auditory, and somatosensory; MRI (magnetic resonance imaging), together with MRI differential prognosis regarding ADEM, MDEM, Lyme ailment, and HTLV-I spastic paraparesis; and puppy (positron emission tomography) and SPECT (single photon emission tomography). Concluding sections hide the gross, microscopic, and electronmicroscopic pathology of MS and the visible method in MS, related to optic and retrobulbar neuritis; fundoscopy, and visible fields. contains bibliographic re ferences and index.
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Additional resources for An Atlas of Multiple Sclerosis
Neuroimaging and the lesion of multiple sclerosis. AJNR 1987; 8:549–52 Thomas P, Walker R, Rudge P, et al. Chronic demyelinating peripheral neuropathy associated with multifocal central nervous system demyelination. Brain 1987;110:53–76 Poser C, Paty D, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis. Ann Neurol 1983;13:227–31 Tsai M-L, Hung K-L. Multiphasic disseminated encephalomyelitis mimicking multiple sclerosis. Brain Dev 1996;18:412–4 Poser C, Roman G, Vernant J-C. Multiple sclerosis or HTLV-I myelitis?
Brain 1994;117:1311–22 Paty D, Poser C. Clinical symptoms and signs of multiple sclerosis. , eds. The Diagnosis of Multiple Sclerosis. New York: Thieme–Stratton, 1984: 27–43 Poser C. Exacerbations, activity and progression in multiple sclerosis. Arch Neurol 1980;37:471–4 Poser C. The course of multiple sclerosis. Arch Neurol 1985;42:1035 Poser C. The pathogenesis of multiple sclerosis. A critical reappraisal. Acta Neuropathol 1986;71: 1–10 Poser C. The peripheral nervous system in multiple sclerosis: A review and pathogenetic hypothesis.
Combined myelin–fat stains. , 1946; reproduced with the permission of Williams & Wilkins Figure 37 Histology (highpower view of the same section as in Figure 36) shows fat-containing macrophages (arrow) scattered among degenerating myelin sheaths. Combined myelin–fat stains. , 1946; reproduced with the permission of Williams & Wilkins Figure 38 Histology (lowpower view) of a fresh plaque from a patient with acute multiple sclerosis shows macrophages filled with ‘neutral’ fat. Oil red–O stain ©1998 CRC Press LLC Figure 39 Histology of an early multiple sclerosis plaque shows gemistocytic astrocytes, seen with H & E–Luxol fast blue (upper) and Golgi (lower) staining Figure 40 Biopsy specimen of a large cerebral plaque that was erroneously diagnosed as an astrocytoma.