By S Prakash
This authoritative reference presents an in depth research of the main updated advancements in synthetic cells, telephone engineering, and telephone remedy. damaged down into 4 sections, the booklet covers the layout, engineering, and makes use of of man-made cells and assesses the medical relevance of synthetic cells and cellphone engineering. Highlights contain liposomes, nanocapsules, stem mobile engineering for remedy, mobile remedy methods for spinal twine harm, remedy of melanoma, insulin supply, and pharmaceutical and to call quite a few. this can be a hugely dynamic region with growing to be curiosity within the use of engineered cells in managed unlock of lively medications and different healing brokers.
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Additional info for Artificial Cells, Cell Engineering and Therapy
Example text
68. de Vos P, van Hoogmoed CG, van Zanten J, Netter S, Strubbe JH, Busscher HJ. Long-term biocompatibility, chemistry, and function of microencapsulated pancreatic islets. Biomaterials 2003; 24(2):305±312. 69. Zhou M, Chen D, Yao Q, Xia Z, Wang C, Zhu H. Microencapsulation of rat islets prolongs xenograft survival in diabetic mice. Chinese Medical Journal (English) 1998; 111(5):394±397. 70. Sun YL, Ma XJ, Zhou DB, Vacek I, Sun AM. Normailization of diabetes in spontaneously diabetic cynomologous monkeys by xenografts of microencapsulated porcine islets without immunosuppression.
Orive G. Cell microencapsulation technology for biomedical purposes: novel insights and challenges. Trends in Pharmacological Sciences 2003; 24(5):207±210. 63. Orive G, Hernandez RM, Gascon AR, Calafiore R, Chang TM, Vos PD et al. Cell encapsulation: promise and progress. Nature Medicine 2003; 9(1):104±107. 64. Chang TMS. Artificial cells for replacement of metabolic organ functions. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology 2003; 31(2):151±161. 65. Chang TMS. Artificial cells for cell and organ replacements.
Alginate beads may be coated by simple suspension of the alginate beads in PLL solution. A 10±30 "m membrane is formed around the beads. The conditions for the formation of this membrane are very mild. Chitosan has been proposed to replace PLL but most research is still based on PLL, especially for encapsulation of animal cells and artificial organs. More recently, immobilization inside a membrane was obtained by dropwise addition of the alginate solution into chitosan solution (interfacial coacervation).
