Read e-book online Biopolymers for medical applications PDF

By Juan M. Ruso, Paula V. Messina

This e-book provides an experimental and computational account of the purposes of biopolymers within the box of medication. Biopolymers are macromolecules produced by means of residing platforms, similar to proteins, polypeptides, nucleic acids, and polysaccharides. Their benefits over polymers produced utilizing artificial chemistry comprise: range, abundance, rather cost-effective, and sustainability. This publication explains options for the construction of other biodevices, corresponding to scaffolds, hydrogels, practical nanoparticles, microcapsules, and nanocapsules. additionally, advancements in nanodrug supply, gene remedy, and tissue engineering are described.

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A. Matthews, K. J. Pawlowski, D. G. Simpson, G. E. Wnek and G. L. Bowlin. 2004. Electrospinning collagen and elastin: preliminary vascular tissue engineering. Front Biosci. 9: C1432. , S. Vahabzadeh and A. Bandyopadhyay. 2013. Bone tissue engineering using 3D printing. Materials Today 16: 496–504. , I. Tissot and F. Lefebvre. 2002. Synthesis and characterization of SiOH-functionalized polymer latexes using methacryloxy propyl trimethoxysilane in emulsion polymerization. Macromolecules 35: 6185–6191.

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Examples can be found of ELP hydrogels that are formed by irradiation (Annabi et al. 2009a), photo-initiation (Almany and Seliktar 2005), aminereactive chemical crosslinking (Annabi et al. 2009b), and enzymatic crosslinking by tissue transglutaminase (McHale et al. 2005; Davis et al. 2010; Collighan and Griffin 2009). The hydrogels have been successfully used for cartilage and intervertebral disc tissue repair, small-diameter vascular grafts, urinary bladders, stem cell matrices, neural guides, stem cell sheets, and post-surgical wound treatment (Simnick et al.

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