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Extra resources for Black's Medical Dictionary: 42nd Edition
The anabolic steroids in therapeutic use include nandrolone and stanozolol. Anabolism Amylose Production by the body of complex molecules like fat and proteins from simpler substances taken in the diet. The name applied to any carbohydrate of the starch group. Anaemia Amyotrophy Loss of muscle bulk and strength caused by a disorder of the nerve that supplies the muscle. The loss is progressive and characterises chronic NEUROPATHY. Patients with DIABETES MELLITUS and MOTOR NEURONE DISEASE (MND) often suffer from amyotrophy as well as spasticity (see SPASTIC) of muscles.
Severe pain is often treated with opioid drugs. g. MORPHINE), whilst newer drugs are man-made. They mimic the action of naturally occurring compounds (ENDORPHINS and ENCEPHALIN) which are found within the brain and spinal cord, and act on receptors to reduce the transmission of painful stimuli within the central nervous system (and possibly peripherally). They tend to produce side-effects of euphoria, respiratory depression, vomiting, constipation and itching. Chronic use or abuse of these drugs may give rise to addiction.
The anaesthetic diffuses into the nerve, blocking it and producing anaesthesia in the area supplied. Small volumes of local anaesthetic are injected into the cerebrospinal fluid through a small-bore needle which has been inserted through the tissues of the back and the dura mater (the outer membrane surrounding the spinal cord). A dense motor and sensory blockade is produced in the lower half of the body. How high up in the body it reaches is dependent on the volume and dose of anaesthetic, the patient’s position and individual variation.