By Benjamin J. Sadock
Completely up-to-date for its 5th variation, Kaplan and Sadock's Pocket instruction manual of medical Psychiatry is still a staple for clinical scholars on psychiatric rotations, psychiatric citizens, practitioners, and psychological healthiness pros. In an easy-to-scan define structure, this renowned quick-reference guide summarizes the etiology, epidemiology, medical features, prognosis, and therapy of all psychiatric issues in adults and youngsters. Psychopharmacologic ideas and prescribing equipment are in brief defined. The booklet is replete with DSM-IV-TR and different tables and contains boxed, highlighted medical tricks. each one bankruptcy ends with particular web page and bankruptcy references to Kaplan and Sadock's accomplished Textbook of Psychiatry, 9th variation.
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Extra info for Kaplan & Sadock's Pocket Handbook of Clinical Psychiatry, 5th Edition
Side effects include leukocytosis, leucopenia, impaired platelet function, mild anemia (both aplastic and hemolytic), and agranulocytosis. Bone marrow and blood element side effects can occur abruptly, even when the dosage has remained constant. Low-potency antipsychotics are most likely to cause agranulocytosis, which is most common bone marrow side effect. These agents may cause hepatocellular injury and intrahepatic biliary stasis (indicated by elevated total and direct bilirubin and elevated transaminases).
B. Dexamethasone suppression test (DST) • Procedure ♦ Give 1 mg of dexamethasone orally at 11 PM. ♦ Measure plasma cortisol at 4 PM and 11 PM the next day (may also take 8 PM sample). ♦ Any plasma cortisol level above 5 &mgr;g/dL is abnormal (although the normal range should be adjusted according to the local assay so that 95% of normals are within the normal range). ♦ Baseline plasma cortisol level may be helpful. 36 • Indications ♦ To help confirm a diagnostic impression of major depressive disorder.
Detectors measure rate at which xenon 133 is cleared from specific brain areas and compare with calculated control to obtain a mean transit time for the tracer. ♦ Gray matter—clears quickly. ♦ White matter—clears slowly. , dementia, ischemia, atrophy). , anxiety, hyperventilation, low carbon dioxide pressure, high rate of CBF). • Test is fast, equipment relatively inexpensive. • Low levels of radiation. • Compared with PET, spatial resolution less, but temporal resolution is better. , when subjected to the Wisconsin Card Sorting Test).