Download e-book for kindle: Lipid Second Messengers by Andrew F. G. Quest, Daniel M. Raben, Robert M. Bell (auth.),

By Andrew F. G. Quest, Daniel M. Raben, Robert M. Bell (auth.), Robert M. Bell, John H. Exton, Stephen M. Prescott (eds.)

Lipids typically were considered as serving services: to shape mobile membranes and to function power shops. over the past twenty years, a brand new function for lipids has taken heart level: lipids can act as signalling molecules. This publication offers with numerous lipids which have been proven to be messengers. best scientists discover all recognized lipid periods other than steroid hormones. Researchers and educators in biochemistry in addition to in molecular and mobile biology will take pleasure in this volume.

Show description

Read or Download Lipid Second Messengers PDF

Best nonfiction_8 books

Douglas Stephen Beck, David Gordon Wilson (auth.)'s Gas-Turbine Regenerators PDF

Regenerative gasoline generators are appealing possible choices to diesel engines and spark­ ignition engines for autos and to diesel engines and combined-cycle en­ gines for energy iteration. concept exhibits regenerative gasoline generators should still in achieving larger thermal efficiencies than these of diesel engines and mixed­ cycle engines.

Download e-book for kindle: Multimedia Services in Intelligent Environments: by George A. Tsihrintzis, Maria Virvou, Lakhmi C. Jain

Multimedia providers at the moment are commonplace in numerous actions within the day-by-day lives of people. similar program components comprise prone that let entry to giant depositories of data, electronic libraries, e-learning and e-education, e-government and e-governance, e-commerce and e-auctions, e-entertainment, e-health and e-medicine, and e-legal companies, in addition to their cellular opposite numbers (i.

Asset Condition, Information Systems and Decision Models by Philip Woodall, Ajith Kumar Parlikad (auth.), Joe E. PDF

Asset situation, info structures and determination versions, is the second one quantity of the Engineering Asset administration overview sequence. The manuscripts supply examples of implementations of asset details platforms in addition to a few functional functions of info for diagnostics and prognostics. The expanding development is in the direction of prognostics instead of diagnostics, therefore the necessity for overview and choice types that advertise the conversion of situation info into prognostic info to enhance life-cycle making plans for engineered resources.

Download e-book for iPad: Information Processing in the Visual Systems of Anthropods: by Rüdiger Wehner (auth.), Rüdiger Wehner (eds.)

It's now in general approved for numerous purposes - morphological in addition to physiologica- that the visible structures of arthropods offer an appropriate version for the learn of data proces­ sing in neuronal networks. not like the neurophysiology of the visible pathway within the frog and the cat that's greater than competently documented, fresh paintings at the compound eye and optical ganglia of spiders, crustaceans, and bugs has scarcely been summarized.

Additional info for Lipid Second Messengers

Sample text

2. Source(s) of Induced Nuclear DAGs Identification of the lipids that serve as the source of the induced nuclear DAGs will provide crucial information required for elucidating the enzymatic mechanisms responsible for the increase in the induced nuclear DAGs, as well as potential physiological roles. , 1991). , 1991), supporting the idea of another phospholipid source. Since it is not possible to selectively radiolabel nuclear phospholipids, potential sources of the induced nuclear DAGs cannot be obtained by analysis of released water-soluble head groups from metabolically labeled cells.

Cysteine-Rich Motifs All PKC isoforms contain at least one cysteine-rich motif. Both cPKCs and nPKCs bind phorbol esters, are activated by DAG, and contain a tandem repeat of two cysteine-rich motifs (Nishizuka, 1992). In PKGy both motifs are required for high-affinity phorbol dibutyrate (PDBu) binding in the presence of calcium (Quest and Bell, 1994b). , 1994). , 1994). , 1993). , 1994a). , 1984). , 1994a,b). , 1994b). , 1989a). , 1994), while the results are controversial for vav. , 1994). , 1992; Maruyama and Brenner, 1991).

In some systems, PC appears to be the predominant, if not exclusive, source of induced diglyceride (reviewed in Billah and Anthes, 1990; Cook and Wakelam, 1992; Exton, 1990). As with PI metabolism, it is not entirely clear that the metabolites derived from PC hydrolysis, PA and diglyceride, are used as the immediate precursors for PI or PC resynthesis. There is also compelling evidence implicating PE metabolism as a signal-transducing component in some 20 Chapter 1 systems. For example, phorbol esters have been shown to stimulate PE hydrolysis, possibly via a PLD-type enzyme, in certain cell types (Kiss and Anderson, 1989).

Download PDF sample

Rated 4.72 of 5 – based on 32 votes