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1898). Zentralbl. , Abt. 1 24, 200-204. Koch, R. (1900). Deut. Med. Wochenschr. 26, 88-90. 24 MARTIN D. YOUNG Kossel, H. (1899). Z. Hyg. Infektionskr. 32, 25-32. Laveran, A. (1880). Bull. Acad. , Paris 9, 1235-1236. Moore, D. , and Lanier, J. E. (1961). Amer. J. Trop. Med. Hyg. 10, 5-9. Shortt, H. , and Garnham, P. C. C. (1948). Brit. Med. J. 1, 1225-1228. Taliaferro, W. , and Taliaferro, L. G. (1934). Amer. J. Hyg. 19, 318-334. Wagner von Jauregg, J. (1922). J. Nerv. Ment. Dis. 55, 369-375. , and Wharton, R.

1962). Proc. Nat. Acad. Sei. U. S. 48, 228. 38 AMBHAN D. FELSENFELD Sanford, K. , Earle, W. , and Likely, G. D. (1948). /. Nat. Cancer Inst. 9, 229. , Bozeman, F. , and Smadel, J. E. (1957). Virology 3, 160. Schein, H. , and Enders, J. F. (1962). Proc. Nat. Acad. Sei. U. S. 48, 1164. , Israeli, C , and Lambert, R. A. (1913). J. Infec. Dis. 13, 294. Stone, H. , Owings, G. C , and Gey, G. O. (1934). Amer. J. Surg. 24, 386. , and Hendee, E. D. (1959). /. Exp. Med. 109, 145. Studnicka, F. K. (1926).

D. Hsiung and Melnick (1957) according to their different behavior in patas and in rhesus monkey cell cultures. The CPE effect of viruses may depend on the species from which the virus was isolated and from which the cell culture was derived. For instance round, large cell clusters are observed after inoculation of some adenoviruses into cells cultured from organs of the same animal species from which the virus was grown. This phenomenon, with special regard to primate species, requires further investigation.

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