By Masud Husain, Jonathan M. Schott
An available, authoritative e-book aimed toward the clinician, The Oxford Textbook of Cognitive Neurology and Dementia covers the dramatic advancements that experience happened in uncomplicated and medical neuroscience in an built-in style.
With contributions from more than a few foreign specialists, this is often the only crucial textbook for clinicians with an curiosity in cognition and dementia - together with neurologists, geriatricians and psychiatrists.
A textbook that's greater than the sum of its constituent elements, it presents a strong technique of bringing jointly varied elements of conceptual figuring out and genuine wisdom in a manner that sometimes can basically come after a long time within the field.
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Extra resources for Oxford textbook of cognitive neurology and dementia
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Gross CG. Aristotle on the Brain. Neuroscientist, 1:245–50, 1995. 16. Gross CG. Galen and the Squealing Pig. 4:216–21, 1998. 17. Rocca J. Galen on the Brain: Anatomical Knowledge and Physiological Speculation in the Second Century ad. Leiden: Brill, 2003. 18. Galen[2nd century]. On Anatomical Procedures:The Later Books. ), Cambridge: Cambridge University Press, 1962. 19. Galen [2nd century]. Galen On the Usefulness of the Parts of the Body. T. ), Ithaca, NY: Cornell University Press, 1968. 20.
It has been recently argued that this assumption is not biologically valid, as lesions in the human brain tend to follow patterns depending, for example, on vascular supply in the case of stroke. 34 Structural MRI data can also be analysed with procedures that provide subject-specific estimated maps of grey matter volume or thickness,35–38 which are more suitable for studying subtle structural changes and, differently from VLMS, do not rely on ‘radiologically visible’ and discrete lesions. Among them, voxel-based morphometry (VBM) involves segmentation of the grey matter, spatial transposition of all the subjects’ images to the same stereotactic space, and ‘modulation’ to obtain voxel-specific values of grey matter density (or volume).
To establish localization and strength of the association between the experimental condition and the measured brain changes, the functional images that have been acquired over time during different conditions and across different subjects need to be realigned and mapped into standard stereotactic, voxel- based spaces. Then, methods allowing statistical inference need to be used. 62 These are then used to compare different conditions and to identify regionally specific changes of signal attributable to the experimental task (Fig.
