By C. L. Dake, E. L. Greve (auth.), E. L. Greve (eds.)
The lawsuits of this symposium on scientific treatment in Glaucoma are divided in 4 significant elements. The pharmacological advent provides the reader a brief description of things which are concerned among management of the drug and its motion on the wanted place within the eye. the hot and intriguing box of drug supply structures could be handled during this half and half II. initially we had requested Ken Richardson to provide a part of the lectures on Membrane expertise and simple features of cholinergic motion. Unfortu nately on the final second he couldn't come. Our thank you visit Gavin Paterson and Klaus Heilmann who have been prepared to take over part of his task. half II on cholinergic motion bargains subsequent to the well known medicines infor mation approximately Ocusert. half III covers the hot advancements within the adrenergic box, together with guanethidine and atenolol. The scientific points of scientific remedy in glaucoma are coated through half IV. Many matters couldn't be dealt with. We disregarded the systemic therapy of glaucoma (diamox, mannitol etc.). We disregarded all unique circumstances and prob lem circumstances. a few questions may be spoke back through the around desk discus sion, such a lot remained unanswered. it truly is transparent that there's sufficient subject-mat ter and curiosity for one more symposium on remedy of glaucoma.
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Extra resources for Symposium on Medical Therapy in Glaucoma, Amsterdam, May 15, 1976
Sample text
B) Therapy of disease when controlled cyclic variation of drug therapy is desirable. c) Delivery of drugs at a rate triggered by a feedback signal from organ or body. 3. Multiple sequenced drug therapy a) Combinations of drugs, each with a precise, predictable, and different delivery rate. b) Drug delivery sequencing. 4. e. postoperative antibiotics, cycloplegics) by inexperienced personnel. e. postoperative and pre-examination cycloplegic/mydriatics, preoperative antibiotics). c) Improving therapy in difficult socio-economic environments.
Pat. 1. Fig. 2. L. eye. pat. 1. 38 shows only a very slow spontaneous reactiviation. Therefore they are called 'irreversible' inhibitors. Mintacol or di-ethyl-p-nitrophenylphosphate is used in 0,25% to 1% solutions. Since the advent of epinephrine and carbonic anhydrase inhibitors its use has been declining. Publications on accelerated cataract formation have given a further decrease in its use. Although quite frequently used in Amsterdam in the past we have not been aware of this cataractogenic effect.
Two of them were excluded because their lOP were consistently less than 22 mm Hg. appl. One patient left the study because of pain after inserting the Ocusert and preferred eye-drop medication. He noticed no congestion or blurring, so that it seems unlikely that there was leakage as reported by Lee et al. (1975). Of the remaining 21 patients 9 were female and the average age was 64 years. The diagnoses were as follows: established glaucoma 15, of which 1 had pigmentary glaucoma; glaucoma suspect 4; low tension glaucoma 1, and secondary glaucoma 1.
