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Extra resources for Viva Voce in Medical Pharmacology
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7. What are the therapeutic uses of carbamazepine? It is used for complex partial seizures may be used for generalized tonic clonic, simple partial seizures, trigeminal and other related neuralgia, mania depressive illness as alternative to lithium, cranial diabetes insipidus. 8. How acetazolamide acts as an antiepileptics? The proposed mechanism of action of acetazolamide a carbonic anhydrase inhibitor that it raises level C02 level in brain and thus lowers pH and thereby raising the threshold of seizure and sedation.
X. Metabolism: Mobilizes Ca2+ from bone and antilipolytic. 5. Mention some of the therapeutic uses of PGs? These are rarely used for availability cost and side effects but indicated for: i. Abortion ii. Induction of labour iii. Cervical priming iv. PPH v. Peptic ulcer vi. To maintain PDA vii. PGI2 to prevent platelet aggregation during hemodialysis and cardiopulmonary bypass and harvest platelets.
What are the adverse effects of antipsychotic drug? These are as follows: i. CNS-Drowsiness, Lethargy, tolerance, increased apetite, seizures may be precipitated. ii. a-adrenergic blockade-Palpitation, difficulties with ejaculation, postural hypotension iii. Endocrinal-Gynaecomastia, Amenorrhoea, Infertility iv. Anticholinergic-Dry mouth, Blurred vision, constipation, urinary hesitancy v. Extrapyramidal disturbances-Parkinsonism, muscular dystonia, Akathisia, Malignant neuroleptic syndrome, Tardive dykinesia.
