By Daniel Le Grange PhD, James Lock MD PhD
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Additional resources for Eating Disorders in Children and Adolescents: A Clinical Handbook
T. (20050. Taste, olfactory, and food texture processing in the brain, and the control of food intake. Physiology and Behavior, 85, 45–56. Rubinow, D. , Schmidt, P. , & Roca, C. A. (1998). Estrogen-serotonin interactions: Implications for affective regulation. Biological Psychiatry, 44(9), 839–850. , & Rotte, M. (2006). Hunger and satiety in anorexia nervosa: fMRI during cognitive processing of food pictures. Brain Research, 1114, 138–148. Saper, C. , Chou, T. , & Elmquist, J. K. (2002). The need to feed: Homeostatic and hedonic control of eating.
Heritability estimates for BN in adulthood. Twin studies of BN in adulthood indicate that it is significantly heritable, with heritability estimates ranging from 28 to 83%. 2). , 2009). The items with the lowest heritability estimates were amenorrhea (16%) and “did others tell you that your low weight was a hazard to your health? (9%),” whereas the highest heritability estimates were found for “weight loss of more than 15 pounds (34%)” and lowest lifetime body mass index (BMI) (33%). 3). This indicates that the symptoms that commonly precede the development of AN and BN are also highly heritable.
2000) (2002) Wade et al. (1999) Wade, Martin, et al. (2000) Klump et al. (2002) Klump, Burt, et al. (2007) Slof-Op't Landt et al. (2008) Klump, Burt, Slof-Op't Landt et al. (2007) et al. 3. Heritability estimates for overall disordered eating in adulthood. Twin studies of overall disordered eating, measured continuously, in adulthood indicate that disordered eating is significantly heritable, with heritability estimates ranging from 34 to 65%. Developmental Twin Studies of Disordered Eating Eating disorder onset often occurs during adolescence, and studies examining genetic and environmental influences on disordered eating from a developmental perspective can provide valuable information regarding mechanisms of onset.